Patient Stories

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a rare genetic disorder that profoundly impacts the lives of patients and their families. This inherited condition can manifest as migraines and mood disorders, and later causes dementia or strokes.

The reality of living with CADASIL or caring for a loved one with the disease can be overwhelming, especially because there is so little information available. In an effort to shed light on the journey and resilience of those affected, we are proud to highlight two powerful CADASIL stories — one from Ki Coale, a patient, and one from Sheila Connor, a family member. These videos offer a glimpse into the lives of individuals navigating the complexities of this condition and capture their motivations for participating in clinical research.